Pearl of Wisdom: Shaping Genomic Therapies & Community Research with Dr. Jocelynn Pearl.

Jocelynn Pearl, a life scientist, podcast host, and advocate for decentralized science, joins Karl and Erum to discuss the future of biotech and the exciting developments happening in the field. Jocelynn shares her experiences in gene editing, specifically with zinc fingers and TALENs, and how the advent of CRISPR has revolutionized the field. She also highlights the significance of epigenome editing and its potential for treating diseases. Jocelynn discusses the concept of decentralized science and its impact on scientific publishing and collaboration. They conclude with a discussion on the future of biotech, where advancements in therapeutics are expected to lead to significant improvements in patient care.

Topics Covered

  • 00:00:00 Discussing Climate Change and Lab-grown Food: Possible Relief for Global Farmers

  • 00:01:24 Unpacking the Benefits and Common Concerns About Lab-grown Food

  • 00:03:56 Addressing Antibiotics in Livestock and the Impact on Grocery Prices

  • 00:05:10 Exploring the Disparity in Subsidies: The Overemphasis on Fossil Fuel and Highways Over Trains

  • 00:07:26 The Promise of Maglev Trains and Quantum Computing: A Peek Into the Future

  • 00:11:35 Bridging Biology and Technology: An Insight into Biotech Consulting

  • 00:14:32 Speculations on Extraterrestrial Contact: Is It Around the Corner?

  • 00:16:19 Women in Leadership: Reflecting on a Three-Year Journey of Empowering Narratives

  • 00:19:48 The Advent of CRISPR: A Landmark in DNA Editing Revolution Since 2010

  • 00:21:50 Unraveling the Role of Epigenome Editing in Disease Therapeutics

  • 00:23:36 The Epigenetic Approach: Modulating Gene Expression Without DNA Cleavage

  • 00:25:24 Enhancing Human Performance: The Untapped Potential of the Epigenome

  • 00:27:14 The Metformin Study: A Crowdfunded Initiative to Understand Population-wide Effects

  • 00:31:10 The Dawn of Decentralized Science: Envisioning the Future Beyond Regulatory Boundaries

  • 00:33:28 Blockchain Meets Science: A Potential Upheaval in Scientific Publishing

  • 00:37:34 Enhancing Drug Development with Advanced Computational Tools and Protein Structure Prediction

  • 00:39:58 The Biotech Horizon: Predictions and Insights from an Industry Expert

  • 00:42:05 The Rise of Targeted Therapeutics: A New Era in Drug Discovery

  • 00:44:54 A Journey Through Time: Memorable Milestones in Challenging Scientific Careers

  • 00:48:03 Jocelynn's Horticultural Hobby: A Deep Dive into House Plants and Avocado Trees

  • 00:50:23 Seattle's Growing Oasis: Figs, Lavender, Vegetables, and Family Bonds

  • 00:54:03 The 'Grow Everything' Hotline and the Passion for Green Living

Topics Covered

Jocelynn Pearl on LinkedIn

World Farmers’ Organization - Anti Lab-grown food statement

Northeast Maglev Trains

LabDAO

Lady Scientist Podcast

Tune Therapeutics

Venture City on Youtube - Mars timelapse 

Astera Institute - Unblocking Scientific Publishing

Golden Age of Medicine - New York Times

For Blood and Money: Billionaires, Biotech, and the Quest for a Blockbuster Drug” by Nathan Vardi. 

Chasing My Cure by David Fajgenbaum

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Unlocking the Gene-ius of AI-Powered Biology: Teselagen's Eduardo Abeliuk